biomedical clinical life sciences

<a href=https://camembert-bio-model.fr/> <img width="300px" src="https://www.camembert-bio-model.fr/authors/camembert-bio/avatar_hu793b92579abd63a955d3004af578ed96_116953_270x270_fill_lanczos_center_3.png"> </a>

CamemBERT-bio : a Tasty French Language Model Better for your Health

CamemBERT-bio is a state-of-the-art french biomedical language model built using continual-pretraining from camembert-base. It was trained on a french public biomedical corpus of 413M words containing scientific documents, drug leaflets and clinical cases extrated from theses and articles. It shows 2.54 points of F1 score improvement on average on 5 different biomedical named entity recognition tasks compared to camembert-base.

Absract

Clinical data in hospitals are increasingly accessible for research through clinical data warehouses, however these documents are unstructured. It is therefore necessary to extract information from medical reports to conduct clinical studies. Transfer learning with BERT-like models such as CamemBERT has allowed major advances, especially for named entity recognition. However, these models are trained for plain language and are less efficient on biomedical data. This is why we propose a new french public biomedical dataset on which we have continued the pre-training of CamemBERT. Thus, we introduce a first version of CamemBERT-bio, a specialized public model for the french biomedical domain that shows 2.54 points of F1 score improvement on average on different biomedical named entity recognition tasks.

<!-- ### Model Sources [optional] -->

<!-- Provide the basic links for the model. -->

<!-- - Website: camembert-bio-model.fr --> <!-- - Paper [optional]: [More Information Needed] --> <!-- - Demo [optional]: [More Information Needed] -->

Training Details

Training Data

<!-- This should link to a Data Card, perhaps with a short stub of information on what the training data is all about as well as documentation related to data pre-processing or additional filtering. -->

Corpus Details Size
ISTEX diverse scientific literature indexed on ISTEX 276 M
CLEAR drug leaflets 73 M
E3C various documents from journals, drug leaflets, and clinical cases 64 M
Total 413 M

Training Procedure

<!-- This relates heavily to the Technical Specifications. Content here should link to that section when it is relevant to the training procedure. -->

We used continual-pretraining from camembert-base. We trained the model using the Masked Language Modeling (MLM) objective with Whole Word Masking for 50k steps during 39 hours with 2 Tesla V100.

Evaluation

<!-- This section describes the evaluation protocols and provides the results. -->

Fine-tuning

For fine-tuning, we utilized Optuna to select the hyperparameters. The learning rate was set to 5e-5, with a warmup ratio of 0.224 and a batch size of 16. The fine-tuning process was carried out for 2000 steps. For prediction, a simple linear layer was added on top of the model. Notably, none of the CamemBERT layers were frozen during the fine-tuning process.

Scoring

To evaluate the performance of the model, we used the seqeval tool in strict mode with the IOB2 scheme. For each evaluation, the best fine-tuned model on the validation set was selected to calculate the final score on the test set. To ensure reliability, we averaged over 10 evaluations with different seeds.

Results

Style Dataset Score CamemBERT CamemBERT-bio
Clinical CAS1 F1 70.50 ± 1.75 73.03 ± 1.29
P 70.12 ± 1.93 71.71 ± 1.61
R 70.89 ± 1.78 74.42 ± 1.49
CAS2 F1 79.02 ± 0.92 81.66 ± 0.59
P 77.3 ± 1.36 80.96 ± 0.91
R 80.83 ± 0.96 82.37 ± 0.69
E3C F1 67.63 ± 1.45 69.85 ± 1.58
P 78.19 ± 0.72 79.11 ± 0.42
R 59.61 ± 2.25 62.56 ± 2.50
Drug leaflets EMEA F1 74.14 ± 1.95 76.71 ± 1.50
P 74.62 ± 1.97 76.92 ± 1.96
R 73.68 ± 2.22 76.52 ± 1.62
Scientific MEDLINE F1 65.73 ± 0.40 68.47 ± 0.54
P 64.94 ± 0.82 67.77 ± 0.88
R 66.56 ± 0.56 69.21 ± 1.32

Environmental Impact estimation

<!-- Total emissions (in grams of CO2eq) and additional considerations, such as electricity usage, go here. Edit the suggested text below accordingly -->

<!-- ## Citation [optional] -->

<!-- If there is a paper or blog post introducing the model, the APA and Bibtex information for that should go in this section. -->

<!-- BibTeX: -->

Citation information

@misc{touchent2023camembertbio,
      title={CamemBERT-bio: a Tasty French Language Model Better for your Health}, 
      author={Rian Touchent and Laurent Romary and Eric de la Clergerie},
      year={2023},
      eprint={2306.15550},
      archivePrefix={arXiv},
      primaryClass={cs.CL}
}

@inproceedings{touchent:hal-04130187,
  TITLE = {{CamemBERT-bio : Un mod{\`e}le de langue fran{\c c}ais savoureux et meilleur pour la sant{\'e}}},
  AUTHOR = {Touchent, Rian and Romary, Laurent and De La Clergerie, Eric},
  URL = {https://hal.science/hal-04130187},
  BOOKTITLE = {{18e  Conf{\'e}rence en Recherche d'Information et Applications \\ 16e Rencontres Jeunes Chercheurs en RI \\ 30e Conf{\'e}rence sur le Traitement Automatique des Langues Naturelles \\ 25e Rencontre des {\'E}tudiants Chercheurs en Informatique pour le Traitement Automatique des Langues}},
  ADDRESS = {Paris, France},
  EDITOR = {Servan, Christophe and Vilnat, Anne},
  PUBLISHER = {{ATALA}},
  PAGES = {323-334},
  YEAR = {2023},
  KEYWORDS = {comptes rendus m{\'e}dicaux ; TAL clinique ; CamemBERT ; extraction d'information ; biom{\'e}dical ; reconnaissance d'entit{\'e}s nomm{\'e}es},
  HAL_ID = {hal-04130187},
  HAL_VERSION = {v1},
}

<!-- [More Information Needed] -->

<!-- APA: -->

<!-- [More Information Needed] -->