biology genomics single-cell model_cls_name:SCANVI scvi_version:0.20.0 anndata_version:0.8.0 modality:rna tissue:Liver annotated:True

Description

Tabula sapiens. An across organ dataset of cell-types in human tissues.

Model properties

Many model properties are in the model tags. Some more are listed below.

model_init_params:

{
    "n_hidden": 128,
    "n_latent": 20,
    "n_layers": 3,
    "dropout_rate": 0.05,
    "dispersion": "gene",
    "gene_likelihood": "nb",
    "latent_distribution": "normal",
    "use_batch_norm": "none",
    "use_layer_norm": "both",
    "encode_covariates": true
}

model_setup_anndata_args:

{
    "labels_key": "cell_ontology_class",
    "unlabeled_category": "unknown",
    "layer": null,
    "batch_key": "donor_assay",
    "size_factor_key": null,
    "categorical_covariate_keys": null,
    "continuous_covariate_keys": null
}

model_summary_stats:

Summary Stat Key Value
n_batch 2
n_cells 2860
n_extra_categorical_covs 0
n_extra_continuous_covs 0
n_labels 13
n_latent_qzm 20
n_latent_qzv 20
n_vars 4000

model_data_registry:

Registry Key scvi-tools Location
X adata.X
batch adata.obs['_scvi_batch']
labels adata.obs['_scvi_labels']
latent_qzm adata.obsm['_scanvi_latent_qzm']
latent_qzv adata.obsm['_scanvi_latent_qzv']
minify_type adata.uns['_scvi_adata_minify_type']
observed_lib_size adata.obs['_scanvi_observed_lib_size']

model_parent_module: scvi.model

data_is_minified: True

Training data

This is an optional link to where the training data is stored if it is too large to host on the huggingface Model hub.

<!-- If your model is not uploaded with any data (e.g., minified data) on the Model Hub, then make sure to provide this field if you want users to be able to access your training data. See the scvi-tools documentation for details. -->

Training data url: https://zenodo.org/api/files/fd2c61e6-f4cd-4984-ade0-24d26d9adef6/TS_Liver_filtered.h5ad

Training code

This is an optional link to the code used to train the model.

Training code url: https://github.com/scvi-hub-references/tabula_sapiens/main.py

References

The Tabula Sapiens: A multi-organ, single-cell transcriptomic atlas of humans. The Tabula Sapiens Consortium. Science 2022.05.13; doi: https: //doi.org/10.1126/science.abl4896